Biothiol probe
WebSep 17, 2024 · Abstract. The selective detection of glutathione (GSH) in vitro and in vivo has attracted great attentions, credited to its important role in life activities and association with a series of diseases. Among all kinds of analytical techniques, the fluorescent probe for GSH detection become prevalent recently because of its ease of operation, high temporal … WebNov 28, 2024 · The probe’s ether bond cleavage by the corresponding biothiol releases the coumarin fluorophore and produces thiol-NBD adducts. The appropriate NBD-derived …
Biothiol probe
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WebApr 1, 2024 · Abstract. Fluorescent probes for biothiols have aroused increasing interest owing to their potential to enable better understanding of the diverse physiological and … WebA novel ratiometric mitochondrial cysteine (Cys)-selective two-photon fluorescence probe has been developed on the basis of a merocyanine as the fluorophore and an acrylate moiety as the biothiol reaction site. The biocompatible and photostable acrylate-functionalized merocyanine probe shows not only a mitochondria-targeting property but …
WebFeb 1, 2024 · Similarly, Yin and Chen introduced biotin into the structure of fluorescein, which can target overexpressed receptors on the surface of cancer cells, designed and created a fluorescent probe 5 targeting tumours for the detection of biothiol. Probe 5 also uses an acryloyl moiety as the reaction site for Cys [32]. By targeting cancer cells that ... WebOct 3, 2024 · Real-time live cell imaging and quantification of biothiol dynamics are important for understanding pathophysiological processes. However, the design and …
WebMar 26, 2024 · However, our probes have cellular toxicity issues arising from the leaving group (LG) that is generated after the reaction of the fluorescent probe and the analytes. … WebAug 5, 2024 · It would be highly desirable to explore near-infrared biothiol-specific fluorescent probes for cancer diagnosis with outstanding specificity. In this study, a …
WebNov 26, 2024 · Fluorescent probes for biothiols have aroused increasing interest owing to their potential to enable better understanding of the diverse physiological and pathological processes related to the biothiol species. BODIPY fluorophores exhibit excellent optical properties, which can be readily tailored by introducing diverse functional units at ...
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